nANO bIOPHYSICS

We are using knowledge and techniques in Physics, Chemistry and Engineering to understand the fundamental phenomena in transport and to develop cutting-edge technologies.

Currently, we are focusing on transport in nanofluidics and building with DNA nanotechnology. Transport in nanofluidics is ubiquitous in many biological processes and underpins many applications such as blue energy harvesting and nanopore sensing technology for single-molecule detection and sequencing. DNA has been repurposed as a building material for creating functional nanoscale structures. By combining nanopore and DNA nanotechnology, we are studying the physics of molecular transport in nanoconfinement. We explore applications in the detection of DNA, RNA and protein molecules with the potential for diagnosis. Moreover, a next-generation data storage approach could be developed based on nanopore sensing and DNA nanostructures.

About Kaikai Chen

Kaikai Chen is an associate professor at the School of Nanoscience and Nanotechnology, University of Chinese Academy of Sciences (UCAS), with the support from the prestigious NSFC Excellent Young Scholars Fund (overseas). Prior to this, he worked as a Research Associate at the Ulrich Keyser’s group at the Cavendish Laboratory, Department of Physics, University of Cambridge, from August 2017 to December 2022. He received his PhD from Tsinghua University in 2017. He has a multidisciplinary background in physics, engineering, and biology. The main research areas are applied physics and biophysics, with a focus on single-molecule methods, biosensors, and biomaterials. He has published more than 20 papers in journals such as Nature Physics, Nature Nanotechnology, Nature Communications, Advanced Materials, ACS Nano, Nano Letters, Advanced Functional Materials, Biophysical Journal, etc. His research results have been featured by Phys.org, Nanowerk, ScienMag, Bioengineer.org, etc. 

Relevant links:     UCAS homepage      Google Scholar          Twitter